Three Rivers (9pm, CBS) - The debut of another new medical show, this one about a transplant team in Pittsburgh and starring Alex O'Loughlin (left). Tonight, a pregnant woman needs a new heart.
Desperate Housewives (9pm, ABC) - Someone strangled Julie last week (and I tried very hard to care). The obvious suspects are from the new family who just moved in -- either the son Julie's tutoring or the creepy ass dad. But that's too obvious, so my guess is that Zach Young has gone nuts again and returned to Wisteria Lane.
My Monkey Baby (9pm, TLC) - I'm officially no longer surprised by any programming on TLC. This show is about a couple raising their pet monkey as a child.
Curb Your Enthusiasm (9pm, HBO) - First night of the Seinfeld reunion story arc. Trying to win back ex-wife Cheryl, Larry agrees to do a Seinfeld reunion show and must convince Jerry Seinfeld, Julia Louis-Dreyfus, Jason Alexander, and Michael Richards to participate.
Entourage (10:30pm, HBO) - The season 6 finale features Matt Damon and Lebron James.
Also noteworthy tonight, the contestants race in Vietnam on Amazing Race (8pm, CBS); Michael Nouri guest stars on Drop Dead Diva (9pm, Lifetime); Oliver Platt guest stars on Bored to Death (9:30pm, HBO); Next Iron Chef (9pm, Food) starts season 2; and of course, Mad Men at 9pm on AMC.