A Gifted Man (8pm, CBS) - Michael is surprised to see an ex-football star whom he once treated now getting help at the clinic because he's homeless.
Chuck (8pm, NBC) - The fifth and final season opens with Chuck (Zachary Levi, left) adapting to changes, such as dealing with an unlikely new Intersect and fronting his freshly minted spy-for-hire business. Carmichael Industries takes on a wealthy thief (Mark Hamill) and a sly investor (Craig Kilborn). Meanwhile, Morgan and Chuck team up to give Sarah a special surprise, and Jeff and Lester launch yet another scheme.
Grimm (9pm, NBC) - In the first episode of this strong new series following a detective who tracks fairy tale monsters, a university student is savagely attacked while jogging, and a mysterious woman visits her nephew to tell him a family secret. Read more in Adrienne's review.
Supernatural (9pm, CW) - Sam and Dean are cloned by two Leviathans who go on a killing spree as the two brothers, which lands the real Sam and Dean on the FBI's most wanted list. Meanwhile, Bobby tries to find a way to kill the Leviathans.
Fringe (9pm, Fox) - The threatening return of the translucent shape-shifters coincides with the reemergence of a former Massive Dynamic scientist (Arye Gross). Meanwhile, Walter gets a visit in the lab from Nina Sharp.
Blue Bloods (10pm, CBS) - Frank deals with a political crisis after Jamie and Renzulli are injured by a church security team that refuses to let them enter a religious center in response to a 911 call.