Smallville (8pm, CW) - In a two-hour series finale, Clark Kent's (Tom Welling, right) 10-year journey to become the Man of Steel culminates as he takes on his adversary Darkseid, who is determined to corrupt Earth and its inhabitants. Meanwhile, Lex Luthor (Michael Rosenbaum) returns to Smallville to confront Kent.

Shark Tank (8pm, ABC) - This is the Season 2 finale??? How many shows are in a season, five? Way too short, ABC. Exhibit A: Tonight someone pitches a toilet-training kit for cats. We need more of this in our lives.

Friday Night Lights (8pm, NBC) - Coach Taylor gives recruitment advice to Vince, four East Dillon students make a pact, and Julie's relationship with a TA gets more complicated.

CSI: NY (9pm, CBS) - Season 7 ends with Mac determined to close his last remaining unsolved case. His newfound focus is triggered by a harrowing near-death experience.

Blue Bloods (10pm, CBS) - This show's strong first season concludes with Frank (Tom Selleck) attempting to take down the secretive Blue Templar police organization after a drug bust exposes some dirty cops.

Smallville (8pm, CW) - Everyone loses their memory after drinking spiked champagne, courtesy of Zatanna, at Clark and Lois's bachelor and bachelorette parties.

Who Do You Think You Are (8pm, NBC) - Kim Cattrall digs into her family roots, centering her investigation on the mysteries surrounding her grandfather. She uncovers an uncomfortable truth and forges new connections with the women in her family.

Fringe (9pm, Fox) - There's a lot of buzz about this episode, which will be heavy on flashbacks. Apparently, Walter (right) recounts the crucial period of time in the 1980s following his initial visit to the alternate universe and the ongoing Cortexiphan tests he was conducting on young children. "Fringe" fans should not miss it.

Your OWN Star (9pm, OWN) - Oprah's search for the next TV star comes to an end tonight. The two finalists must create pilots for their own shows, with Mark Burnett as their mentor, and Oprah crowns a winner.

DC Cupcakes (10pm, TLC) - In the Season 2 premiere, a 9-foot cupcake sculpture of a glow-in-the-dark guitar is constructed for a sweet 16 party. A second episode airs at 10:30.

Bar Karma (10pm, Current TV) - Sonja Sohn (Kima from "The Wire") guest-stars as “Lucy,” a famous actress who is summoned to Bar Karma in the middle of a surgical procedure. Will she make it out of the operating room alive? The star of "Bar Karma" is from Chapel Hill.

Portlandia (10:30pm, IFC) - The first season finale of the hilariously bizarre send-up of a couple of pretentious hipsters in Portland features Fred Armisen and Carrie Brownstein holding tryouts for a new Portland baseball team. Here's a sneak peek.

Smallville (8pm, CW) - Anti-superhero citizens attack the Green Arrow as he tries to stop a mugging, and Clark learns the attackers all have a darkness tattoo. Elsewhere, Carter Hall and Star Girl help Clark pursue Slade, who has kidnapped Lois.

The Good Guys (9pm, Fox) - In the Season 1 (and maybe series) finale, Jack and Dan respond to a dine-and-dash theft at a restaurant, and learn that a dirty cop may have murdered an informant against a Mafia kingpin.

Supernatural (9pm, CW) - Dean seeks out Death to get Sam's soul back, but Sam decides he doesn't want it returned and tries a protective spell to keep his soul out of his body.

TeenNick HALO Awards (9pm, Nick) - Nick Cannon hosts the second annual celebration honoring four teens who have taken leadership roles to help their communities. Each honoree meets with a celebrity, including Mariah Carey, Ashton Kutcher, Rosario Dawson, and Wyclef Jean.

Smallville (8pm, CW) - Lois Lane (Erica Durance, left) views a video her mom Ella Lane (Teri Hatcher) made for her before her death. The tape prompts Lois to make a major decision about Clark, which leads to her  encountering Jor-El and Lara at the Fortress (note to youngsters: Hatcher played Lois Lane in the 90s TV show "Lois & Clark").

Supernanny (8pm, ABC) - Jo helps a couple so preoccupied with trying to discipline their three older children (often by putting hot sauce on their lips) that they are in danger of neglecting their baby. They really should have named this show "People Who Shouldn't Reproduce."

Blue Bloods (10pm, CBS) - Jamie witnesses a crime in Chinatown and the suspect is killed while Jamie pursues him. Danny investigates and must solve the case to prevent Jamie from being the target of an Internal Affairs probe.

Sanctuary (10pm, Syfy) - Kate gains superpowers when an Abnormal adheres itself to her after gunmen breach the Sanctuary in a bid to steal the creature.

Real Time with Bill Maher (10pm, HBO) - The eighth season comes to a close with guests Nora Ephron, Michael Moore, Jessica Yellin, former Arkansas governor Mike Huckabee, and Pennsylvania Rep. Joe Sestak.

Smallville (8pm, CW) - Lois Lane's mom and dad visit unexpectedly for Thanksgiving. Tensions rise when the General (Michael Ironside) bad-mouths superheroes and informs Clark Kent of his efforts to pass the vigilante registration act. Meanwhile, Rick Flagg plots to kill the General.

CSI: NY (9pm, CBS) - Mac searches for a sniper who is firing from city rooftops. The shootings force him to relive a disturbing abduction case that may have created one of the deadliest foes the CSIs have faced. John Larroquette guest stars.

The Good Guys (9pm, Fox) - A fainting spell confines Dan to his desk at the onset of a case involving a painting that was stolen from a doctor's house.

Operation Wild (9pm, Planet Green) - In the second season premiere, an 8-foot-long crocodile brings an officer to a family's residence. In the 9:30pm ep, rescued baby sea turtles are released back into the wild, and an illegal scallop harvesting is addressed.

Teach: Tony Danza (10pm, A&E) - Tony catches two students cheating, mediates a fight between friends in his class, and is asked to chaperone the homecoming dance.

The Walking Dead (10pm, AMC) - A repeat of Sunday night's stunning premiere episode. Read more here.

Conspiracy Theory with Jesse Ventura (10pm, TruTV) - Jesse investigates the reasons behind the economic downturn.

Sanctuary (10pm, Syfy) - Nikola Tesla sends a distress call to the team and they track him to the Colombian highlands, where they encounter deadly multipedes. Meanwhile, Bigfoot and Kate learn that a long-time friend has been murdered in Old City.

Smallville (8pm, CW) - Cat Grant (Keri Lynn Pratt) is hired by the Daily Planet to replace Lois, who has left for Egypt. When Clark saves Cat from an assassin named Deadshot (Bradley Stryker) he uncovers a plot against the Blur.

Medium (8pm, CBS) - As she probes a series of slayings, Allison begins noticing bizarre symbols materializing above folks' heads and concludes the floating figures could be a mechanism for matching people to their soul mates. Tony Hale and Lana Parrilla guest star.

Blue Bloods (10pm, CBS) - This new Tom Selleck family cop drama smoked its competitors last week in the ratings. Tonight, the Reagans weigh the pros and cons of vigilantism when a man with a police record takes action against a criminal who is terrorizing riders on a subway.

The Increasingly Poor Decisions of Todd Margaret (10pm, IFC) - A new office comedy about a hapless U.S. transplant working in London, created by and starring David Cross. In the first episode, Todd is promoted to sales rep and put in charge of the launch of a new energy drink, Thunder Muscle, which is from North Korea and contains some suspect ingredients.

Outlaw (10pm, NBC) - Garza advocates for an emotionally vacant mother who accidentally killed her baby daughter by leaving the infant in a hot car. Jay Mohr guest stars.

Teach: Tony Danza (10pm, A&E) - A new seven-part series following actor Tony Danza as he teaches sophomore English at Philadelphia's Northeast High School. He also signs up to be an assistant football coach in an attempt to bond with the players in his class. Read more about Danza's show.

Medium (8pm, CBS) - Season 7 opens with Allison and daughter Bridgette sharing the same dream, which revolves around a missing homeless man. Before long, mother and daughter swap personalities, "Freaky Friday" style.

Smallville (8pm, CW) - Has it been ten seasons already? In tonight's opener, Lois saves Clark's life by removing the blue kryptonite incapacitating him. Elsewhere, Chloe hunts for Oliver while Tess finds herself in a LuthorCorp lab. Also, Jonathan returns to the farm with a message for Clark.

CSI: NY (9pm, CBS) - New cast member Sela Ward (left) is introduced in tonight's seventh season premiere, discovering the body of a young woman who was murdered somewhere in the New York crime lab building.

Good Guys (9pm, Fox) - "Good Guys" returns tonight with the second half of their first season. Dan funds and off-the-books sting operation with money he "borrowed" from Narcotics, which inadvertently finances a jailbreak that Dan and Jack must stop.

Keep reading for more premiere info, including Tom Selleck in "Blue Bloods."

Smallville (8pm, The CW) - In a special two-hour episode called "Absolute Justice," the Justice Society of America has to save the world from a murderous former member, Icicle. Check out Doctor Fate and Star Girl!

Ghost Whisperer (8pm, CBS) - Criminally underused on "Drop Dead Diva," Margaret Cho guest stars on "Ghost Whisperer" as an occult professor who is being stalked by a secret admirer ghost.

Shark Tank (9pm, ABC) - I. Love. This. Show. Tonight: liquid llama fertilzer, message balls, a bendable geometry toy, and a hands-free umbrella. I would fund all that crap.

Caprica (9pm, Syfy) - Amanda's public admission about Zoe's role in the bombing ignites a backlash against the Graystones and creates tension for Lacy at school. Meanwhile, Zoe plots her next move. 

Law & Order (8pm, NBC) - "Law & Order" enters its 20th season, as well as a new night and earlier timeslot. Tonight, a law professor is scrutinized when a war veteran is found dead in a university parking garage. Later this season, our beloved L-T, Liet. Anita Van Buren (S. Epatha Merkerson, left) will battle cancer.

Brothers (8pm, Fox) - A brand new show starring former NFL defensive end Michael Strahan as a broke football player who moves back home with this brother, played by Daryl "Chill" Mitchell, his mom, CCH Pounder, and his dad, Carl Weathers. Great cast!

Smallville (8pm, CW) - "Smallville" starts season nine on a different night. Tonight, Jor-El tells Clark to end things with Lois, but the heart wants what it wants. Brian Austin Green joins the cast as a new reporter working with Lois.

Ghost Whisperer (8pm, CBS) - Melinda delivers a tiny little ghost whisperer of her very own in tonight's premiere, which is also directed by Jennifer Love Hewitt. The show then takes a "Desperate Houswives" style leap five years into the future.

Medium (9pm, CBS) - The second half of CBS's Friday Ghost Block features NBC's castoff thriller starring Patricia Arquette. The show's producers say there will be no changes to the show, even though it's skipping to a new network. Tonight's premiere picks up four months after last season's finale, and Allison is out of her coma. But will her powers be the same?

Dollhouse (9pm, Fox) - Season two and Echo's first mission is to marry a British businessman linked to a former FBI agent's open case.

Numb3rs (10pm, CBS) - In tonight's premiere, we'll find out if Amita accepted Charlie's marriage proposal. In other business, the team is protecting a political activist who may be the target of a sniper.

Real Time with Bill Maher (10pm, HBO) - This isn't a season premiere, but one of Bill's guests tonight is former New York Governor Eliot Spitzer. Don't expect Maher to castigate Spitzer for the cheating, but still, it should be interesting.